A possible monosynaptic pathway links the pedunculopontine tegmental nucleus to thalamostriatal neurons in the hooded rat
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چکیده
منابع مشابه
Reward prediction error computation in the pedunculopontine tegmental nucleus neurons.
In this article, we address the role of neuronal activity in the pathways of the brainstem-midbrain circuit in reward and the basis for believing that this circuit provides advantages over previous reinforcement learning theory. Several lines of evidence support the reward-based learning theory proposing that midbrain dopamine (DA) neurons send a teaching signal (the reward prediction error sig...
متن کاملEvaluation of nicotinic receptor of pedunculopontine tegmental nucleus in central cardiovascular regulation in anesthetized rat
Objective(s): Cholinergic neurons are important neurons in the Pedunculopontine tegmental nucleus (PPT). In this study, nicotinic receptor of the PPT in central cardiovascular regulation in the anesthetized rat was evaluated. Materials and Methods: Saline, acetylcholine (Ach; doses: 90 and 150 nmol), hexamethonium (Hexa; doses: 100 and 300 nmol) and higher doses of Hexa (300 nmol) + Ach (150 nm...
متن کاملPedunculopontine tegmental nucleus neurons provide reward, sensorimotor, and alerting signals to midbrain dopamine neurons.
Dopamine (DA) neurons in the midbrain are crucial for motivational control of behavior. However, recent studies suggest that signals transmitted by DA neurons are heterogeneous. This may reflect a wide range of inputs to DA neurons, but which signals are provided by which brain areas is still unclear. Here we focused on the pedunculopontine tegmental nucleus (PPTg) in macaque monkeys and charac...
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Introduction: Although formalin-induced activity in primary afferent fibers and spinal dorsal horn is well described, the midbrain neural basis underlying each phase of behavior in formalin test has not been clarified. The present study was designed to investigate the nucleus cuneiformis (CnF) neuronal responses during two phases after subcutaneous injection of formalin into the hind paw...
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ژورنال
عنوان ژورنال: Archives of Histology and Cytology
سال: 2007
ISSN: 0914-9465,1349-1717
DOI: 10.1679/aohc.70.207